{"id":24,"date":"2007-06-04T23:58:29","date_gmt":"2007-06-04T23:58:29","guid":{"rendered":"http:\/\/brainybehavior.com\/blog\/?p=24"},"modified":"2007-06-04T23:58:29","modified_gmt":"2007-06-04T23:58:29","slug":"acute-respiratory-distress-syndrome","status":"publish","type":"post","link":"https:\/\/www.brainybehavior.com\/blog\/2007\/06\/acute-respiratory-distress-syndrome\/","title":{"rendered":"Acute Respiratory Distress Syndrome"},"content":{"rendered":"<div class=\"twyvb69f2b52d6ca6d\" ><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- Mobile in post -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:inline-block;width:320px;height:100px\"\r\n     data-ad-client=\"ca-pub-0039142346952764\"\r\n     data-ad-slot=\"1620587573\"><\/ins>\r\n<script>\r\n(adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><\/div><style type=\"text\/css\">\r\n.twyvb69f2b52d6ca6d {\r\nmargin: 5px; padding: 0px;\r\n}\r\n@media screen and (min-width: 1201px) {\r\n.twyvb69f2b52d6ca6d {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 993px) and (max-width: 1200px) {\r\n.twyvb69f2b52d6ca6d {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 769px) and (max-width: 992px) {\r\n.twyvb69f2b52d6ca6d {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 768px) and (max-width: 768px) {\r\n.twyvb69f2b52d6ca6d {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (max-width: 767px) {\r\n.twyvb69f2b52d6ca6d {\r\ndisplay: block;\r\n}\r\n}\r\n<\/style>\r\n<p>Acute respiratory distress syndrome is a common cause of mortality and morbidity, affecting an estimated 150,000 people per year in the United States (Rubenfeld, Doyle, &amp; Matthay, 1995) however, recent evidence suggests the incidence may be higher (Rubenfeld, 2003). Compared to 20 years ago mortality has decreased from 80% to 30% of ARDS participants (Milberg, Davis, Steinberg, &amp; Hudson, 1995; Brower et al., 2000) resulting in approximately 100,000 people who survive ARDS each year in the United States (Bersten, Edibam, Hunt, &amp; Moran, 2002). Acute respiratory distress syndrome occurs in response to a variety of insults including sepsis, trauma, pneumonia, massive transfusion and other medical\/surgical conditions. Treatment of ARDS requires aggressive supportive care including positive pressure ventilation (Brower et al., 2000) and increased oxygen concentrations with risks of barotrauma, oxygen toxicity, and nosocomial infection.<\/p>\n<p>Acute respiratory distress syndrome may be a consequence of multiple organ system dysfunction, including the central nervous system (Bell, Coalson, Smith, &amp; Johanson, 1983; Montgomery, Stager, Carrico, &amp; Hudson, 1985). Participants who survive ARDS are at risk for neuropsychological deficits (Hopkins et al., 1999; Rothenhausler, Ehrentraut, Schelling, &amp; Kapfhammer, 2001; Al-Saidi et al., 2003; Hopkins, Weaver, Chan, &amp; Orme, 2004) 6 to 12 months following hospital discharge. Approximately 33% of general medical ICU survivors, some with ARDS, have cognitive impairments (Jackson et al., 2003) 6 months after hospital discharge. In 1999, Hopkins and colleagues found that 45% of ARDS survivors had neurocognitive impairments including impaired memory, attention, concentration, mental processing speed, and global intellectual decline one year post-discharge.<\/p>\n<p>Others have since made similar observations (Marquis et al. 2000; Rothenhausler et al., 2001; Al-Saidi et al., 2003; Jackson et al., 2003). The prevalence of neurocognitive impairments varies from 25% (Rothenhausler et al., 2001) to 78% in participants with more severe ARDS (Hopkins et al., 1999). Neurocognitive impairments are a major determinant in return to work, work productivity, and life satisfaction following ARDS (Rothenhausler et al., 2001).<\/p>\n<p align=\"center\">\u00a0<strong>References<\/strong><\/p>\n<p align=\"left\">Al-Saidi, F., McAndrews, M. P., Cheunt, A. M., Tansey, C. M., Matte-Martyn, A., Diaz-Granados, N., et al. (2003). Neuropsychological sequelae in ARDS survivors. American Journal of Respiratory and Critical Care Medicine, 167, A737.<\/p>\n<p align=\"left\">Bell, R. C., Coalson, J. J., Smith, J. D., &amp; Johanson, W. G., Jr. (1983). Multiple organ system failure and infection in adult respiratory distress syndrome. Annals of Internal Medicine, 99, 293\u2013298.<\/p>\n<p align=\"left\">Bersten, A. D., Edibam, C., Hunt, T., &amp; Moran, J. (2002). Incidence and mortality of acute lung injury and the acute respiratory distress syndrome in three Australian States. American Journal of Respiratory and Critical Care Medicine, 165, 443\u2013448.<\/p>\n<p align=\"left\">Brower, R. G., Matthay, M. A., Morris, A., Schoenfeld, D., Thompson, B. T., &amp; Wheeler, A. (2000). Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. New England Journal of Medicine, 342, 1301\u20131308.<\/p>\n<p align=\"left\">Hopkins, R. O., Weaver, L. K., Chan, K. J., &amp; Orme, J. F. (2004). Quality of life, emotional, and cognitive function following acute respiratory distress syndrome. Journal of the International Neuropsychological Society, 10, 1005\u20131017.<\/p><div class=\"uhxqp69f2b52d6cac2\" ><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\n<!-- Mobile in post -->\n<ins class=\"adsbygoogle\"\n     style=\"display:inline-block;width:320px;height:100px\"\n     data-ad-client=\"ca-pub-0039142346952764\"\n     data-ad-slot=\"1620587573\"><\/ins>\n<script>\n(adsbygoogle = window.adsbygoogle || []).push({});\n<\/script><\/div><style type=\"text\/css\">\r\n.uhxqp69f2b52d6cac2 {\r\nmargin: 5px; padding: 0px;\r\n}\r\n@media screen and (min-width: 1201px) {\r\n.uhxqp69f2b52d6cac2 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 993px) and (max-width: 1200px) {\r\n.uhxqp69f2b52d6cac2 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 769px) and (max-width: 992px) {\r\n.uhxqp69f2b52d6cac2 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 768px) and (max-width: 768px) {\r\n.uhxqp69f2b52d6cac2 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (max-width: 767px) {\r\n.uhxqp69f2b52d6cac2 {\r\ndisplay: block;\r\n}\r\n}\r\n<\/style>\r\n\n<p align=\"left\">Hopkins, R. O., Weaver, L. K., Pope, D., Orme, J. F., Bigler, E. D., &amp; Larson-Lohr, V. (1999). Neuropsychological sequelae and impaired health status in survivors of severe acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine, 160, 50\u201356.<\/p>\n<p align=\"left\">Jackson, J. C., Hart, R. P., Gordon, S. M., Shintani, A., Truman, B., May, L., et al. (2003). Six-month neuropsychological outcome of medical intensive care unit participants. Critical Care Medicine, 31, 1226\u20131234.<\/p>\n<p align=\"left\">Marquis, K., Curtis, J., Caldwell, E., Davidson, T., Davis, J., Sanchez, P., et al. (2000). Neuropsychological sequelae in survivors of ARDS compared with critically ill control participants. American Journal of Respiratory and Critical Care Medicine, 161, A383.<\/p>\n<p align=\"left\">Milberg, J. A., Davis, D. R., Steinberg, K. P., &amp; Hudson, L. D. (1995). Improved survival of participants with acute respiratory distress syndrome (ARDS): 1983-1993. Journal of the American Medical Association, 273, 306\u2013309.<\/p>\n<p align=\"left\">Montgomery, A. B., Stager, M. A., Carrico, C. J., &amp; Hudson, L. D. (1985). Causes of mortality in participants with the adult respiratory distress syndrome. American Review of Respiratory Disease, 132, 485\u2013489.<\/p>\n<p align=\"left\">Rothenhausler, H. B., Ehrentraut, S., Stoll, C., Schelling, G., &amp; Kapfhammer, H. P. (2001). The relationship between cognitive performance and employment and health status in long-term survivors of the acute respiratory distress syndrome: Results of an exploratory study. General Hospital Psychiatry, 23, 90\u201396.<\/p>\n<p align=\"left\">Rubenfeld, G. D. (2003). Epidemiology of acute lung injury. Critical Care Medicine, 31, S276\u2013S284.<\/p>\n<p align=\"left\">Rubenfeld, G. D., Doyle, R. L., &amp; Matthay, M. A. (1995). Evaluation of definitions of ARDS. American Journal of Respiratory and Critical Care Medicine, 151, 1270\u20131271.<\/p>\n<div class=\"tbrvx69f2b52d6caec\" ><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- Mobile in post -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:inline-block;width:320px;height:100px\"\r\n     data-ad-client=\"ca-pub-0039142346952764\"\r\n     data-ad-slot=\"1620587573\"><\/ins>\r\n<script>\r\n(adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><\/div><style type=\"text\/css\">\r\n.tbrvx69f2b52d6caec {\r\nmargin: 5px; padding: 0px;\r\n}\r\n@media screen and (min-width: 1201px) {\r\n.tbrvx69f2b52d6caec {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 993px) and (max-width: 1200px) {\r\n.tbrvx69f2b52d6caec {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 769px) and (max-width: 992px) {\r\n.tbrvx69f2b52d6caec {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 768px) and (max-width: 768px) {\r\n.tbrvx69f2b52d6caec {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (max-width: 767px) {\r\n.tbrvx69f2b52d6caec {\r\ndisplay: block;\r\n}\r\n}\r\n<\/style>\r\n","protected":false},"excerpt":{"rendered":"<p>Acute respiratory distress syndrome is a common cause of mortality and morbidity, affecting an estimated 150,000 people per year in the United States (Rubenfeld, Doyle, &amp; Matthay, 1995) however, recent evidence suggests the incidence may be higher (Rubenfeld, 2003). Compared to 20 years ago mortality has decreased from 80% to 30% of ARDS participants (Milberg, &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.brainybehavior.com\/blog\/2007\/06\/acute-respiratory-distress-syndrome\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Acute Respiratory Distress Syndrome&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20,19,24,16,9],"tags":[],"class_list":["post-24","post","type-post","status-publish","format-standard","hentry","category-brain-damage","category-brain-injury","category-cognition","category-neuropsychology","category-psychology"],"_links":{"self":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts\/24","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/comments?post=24"}],"version-history":[{"count":0,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts\/24\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/media?parent=24"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/categories?post=24"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/tags?post=24"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}