{"id":280,"date":"2008-12-04T18:52:17","date_gmt":"2008-12-04T23:52:17","guid":{"rendered":"http:\/\/www.brainybehavior.com\/blog\/?p=280"},"modified":"2008-12-05T14:52:06","modified_gmt":"2008-12-05T19:52:06","slug":"patient-hms-passing","status":"publish","type":"post","link":"https:\/\/www.brainybehavior.com\/blog\/2008\/12\/patient-hms-passing\/","title":{"rendered":"Patient HM&#8217;s Passing"},"content":{"rendered":"<div class=\"dmzzi69f298ab56ab8\" ><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- Mobile in post -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:inline-block;width:320px;height:100px\"\r\n     data-ad-client=\"ca-pub-0039142346952764\"\r\n     data-ad-slot=\"1620587573\"><\/ins>\r\n<script>\r\n(adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><\/div><style type=\"text\/css\">\r\n.dmzzi69f298ab56ab8 {\r\nmargin: 5px; padding: 0px;\r\n}\r\n@media screen and (min-width: 1201px) {\r\n.dmzzi69f298ab56ab8 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 993px) and (max-width: 1200px) {\r\n.dmzzi69f298ab56ab8 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 769px) and (max-width: 992px) {\r\n.dmzzi69f298ab56ab8 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 768px) and (max-width: 768px) {\r\n.dmzzi69f298ab56ab8 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (max-width: 767px) {\r\n.dmzzi69f298ab56ab8 {\r\ndisplay: block;\r\n}\r\n}\r\n<\/style>\r\n<p>On Tuesday, December 2, 2008, Henry M., the most famous patient in modern neuroscience research and literature, passed away. He was 82.\u00a0In 1953, H.M. had an experimental brain\u00a0operation to try to stop his frequent seizures; his medial temporal lobes were resected bilaterally, with significant portions of his amygdalas and hippocampi in both cerebral hemispheres removed (parts of the brain are still resected in intractable epilepsy cases, however\u00a0neurosurgeons\u00a0do not perform that exact surgery any more because of the negative effects). His seizures stopped but immediately after the operation he had a severe anterograde\u00a0amnesia. This means that from when he received the operation at age 27, he was unable to establish new memories for world events and for general information.<a href=\"http:\/\/www.brainybehavior.com\/blog\/wp-content\/uploads\/2008\/12\/hms_brain.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-281\" title=\"HM's Brain\" src=\"http:\/\/www.brainybehavior.com\/blog\/wp-content\/uploads\/2008\/12\/hms_brain-300x280.jpg\" alt=\"\" width=\"300\" height=\"280\" srcset=\"https:\/\/www.brainybehavior.com\/blog\/wp-content\/uploads\/2008\/12\/hms_brain-300x280.jpg 300w, https:\/\/www.brainybehavior.com\/blog\/wp-content\/uploads\/2008\/12\/hms_brain.jpg 408w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>His amnesia became the focus of much scientific study from after his operation until the present.\u00a0No one patient has been studied more in the 20th and 21st centuries than H.M. His memory impairment was also interesting because his overall intellectual abilities were still intact as was his personality. Neuropsychologists and neuroscientists will forever be grateful for the things they learned from H.M.<\/p><div class=\"kakjb69f298ab56b0a\" ><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\n<!-- Mobile in post -->\n<ins class=\"adsbygoogle\"\n     style=\"display:inline-block;width:320px;height:100px\"\n     data-ad-client=\"ca-pub-0039142346952764\"\n     data-ad-slot=\"1620587573\"><\/ins>\n<script>\n(adsbygoogle = window.adsbygoogle || []).push({});\n<\/script><\/div><style type=\"text\/css\">\r\n.kakjb69f298ab56b0a {\r\nmargin: 5px; padding: 0px;\r\n}\r\n@media screen and (min-width: 1201px) {\r\n.kakjb69f298ab56b0a {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 993px) and (max-width: 1200px) {\r\n.kakjb69f298ab56b0a {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 769px) and (max-width: 992px) {\r\n.kakjb69f298ab56b0a {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 768px) and (max-width: 768px) {\r\n.kakjb69f298ab56b0a {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (max-width: 767px) {\r\n.kakjb69f298ab56b0a {\r\ndisplay: block;\r\n}\r\n}\r\n<\/style>\r\n\n<p>The New York Times has a very nice <a href=\"http:\/\/www.nytimes.com\/2008\/12\/05\/us\/05hm.html?_r=2&amp;hp=&amp;adxnnl=1&amp;adxnnlx=1228482103-YdjmJ\/Cq75huwl48A8hp0A\">article about H.M<\/a>.<\/p>\n<div class=\"pkhta69f298ab56b2f\" ><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- Mobile in post -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:inline-block;width:320px;height:100px\"\r\n     data-ad-client=\"ca-pub-0039142346952764\"\r\n     data-ad-slot=\"1620587573\"><\/ins>\r\n<script>\r\n(adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><\/div><style type=\"text\/css\">\r\n.pkhta69f298ab56b2f {\r\nmargin: 5px; padding: 0px;\r\n}\r\n@media screen and (min-width: 1201px) {\r\n.pkhta69f298ab56b2f {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 993px) and (max-width: 1200px) {\r\n.pkhta69f298ab56b2f {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 769px) and (max-width: 992px) {\r\n.pkhta69f298ab56b2f {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 768px) and (max-width: 768px) {\r\n.pkhta69f298ab56b2f {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (max-width: 767px) {\r\n.pkhta69f298ab56b2f {\r\ndisplay: block;\r\n}\r\n}\r\n<\/style>\r\n","protected":false},"excerpt":{"rendered":"<p>On Tuesday, December 2, 2008, Henry M., the most famous patient in modern neuroscience research and literature, passed away. He was 82.\u00a0In 1953, H.M. had an experimental brain\u00a0operation to try to stop his frequent seizures; his medial temporal lobes were resected bilaterally, with significant portions of his amygdalas and hippocampi in both cerebral hemispheres removed &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.brainybehavior.com\/blog\/2008\/12\/patient-hms-passing\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Patient HM&#8217;s Passing&#8221;<\/span><\/a><\/p>\n","protected":false},"author":19,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12,30,18,16,38,126],"tags":[148,149,253,150],"class_list":["post-280","post","type-post","status-publish","format-standard","hentry","category-brain","category-hippocampus","category-memory","category-neuropsychology","category-neuroscience","category-neurosurgery","tag-amnesia","tag-hm","tag-memory","tag-seizures"],"_links":{"self":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts\/280","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/comments?post=280"}],"version-history":[{"count":2,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts\/280\/revisions"}],"predecessor-version":[{"id":283,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts\/280\/revisions\/283"}],"wp:attachment":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/media?parent=280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/categories?post=280"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/tags?post=280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}