{"id":533,"date":"2015-09-04T21:31:31","date_gmt":"2015-09-05T02:31:31","guid":{"rendered":"http:\/\/www.brainybehavior.com\/blog\/?p=533"},"modified":"2015-09-04T21:33:03","modified_gmt":"2015-09-05T02:33:03","slug":"memory-problems-in-some-with-parkinsons-disease","status":"publish","type":"post","link":"https:\/\/www.brainybehavior.com\/blog\/2015\/09\/memory-problems-in-some-with-parkinsons-disease\/","title":{"rendered":"Memory Problems in Some With Parkinson&#8217;s Disease"},"content":{"rendered":"<div class=\"omfgt6a27e40af0b7d\" ><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- Mobile in post -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:inline-block;width:320px;height:100px\"\r\n     data-ad-client=\"ca-pub-0039142346952764\"\r\n     data-ad-slot=\"1620587573\"><\/ins>\r\n<script>\r\n(adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><\/div><style type=\"text\/css\">\r\n.omfgt6a27e40af0b7d {\r\nmargin: 5px; padding: 0px;\r\n}\r\n@media screen and (min-width: 1201px) {\r\n.omfgt6a27e40af0b7d {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 993px) and (max-width: 1200px) {\r\n.omfgt6a27e40af0b7d {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 769px) and (max-width: 992px) {\r\n.omfgt6a27e40af0b7d {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 768px) and (max-width: 768px) {\r\n.omfgt6a27e40af0b7d {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (max-width: 767px) {\r\n.omfgt6a27e40af0b7d {\r\ndisplay: block;\r\n}\r\n}\r\n<\/style>\r\n<p align=\"left\">From a <a href=\"https:\/\/ufhealth.org\/news\/2015\/uf-researchers-find-memory-problems-some-people-parkinson-s-disease\">recent news release<\/a>\u00a0by Jill Pease at the University of Florida.<\/p>\n<p align=\"left\">Using a combination of neuropsychological testing and brain imaging, University of Florida researchers have discovered that in a group of recently-diagnosed patients with Parkinson\u2019s disease, about one quarter have significant memory problems.<\/p>\n<p align=\"left\">Parkinson\u2019s disease is commonly known as a movement disorder that leads to tremors and muscle rigidity, but there is growing recognition of cognitive problems associated with the disease. One of the most common is slower thinking speed that causes patients to have trouble quickly retrieving information. The UF study identifies a subset of patients who have a different kind of cognitive issue \u2014 memory problems, or difficulty learning and retaining new information.<\/p>\n<p align=\"left\">The findings were published July 24 in the journal <a href=\"http:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0133792\">PLOS ONE<\/a>.<\/p>\n<p align=\"left\">\u201cWhile a large proportion of people with Parkinson\u2019s will experience slower thinking speed, which may make them less quick to speak or have difficulty doing two things at once, we now know that there are a subset of individuals with Parkinson\u2019s disease who have memory problems,\u201d said <a href=\"http:\/\/chp.phhp.ufl.edu\/people\/core-faculty\/catherine-price-phd\/\">Catherine Price, Ph.D.<\/a>, the study\u2019s senior author and an associate professor in the <a href=\"http:\/\/chp.phhp.ufl.edu\/\">UF College of Public Health and Health Professions\u2019 department of clinical and health psychology<\/a>, part of UF Health. \u201cIt is important to recognize which people have issues with learning and memory so we can improve diagnostic accuracy and determine if they would benefit from certain pharmaceutical or behavioral interventions.\u201d<\/p>\n<p align=\"left\">For the UF study, 40 people in the early stages of Parkinson\u2019s disease and 40 healthy older adults completed neuropsychological assessments and verbal memory tests.<\/p><div class=\"ixikq6a27e40af0be6\" ><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\n<!-- Mobile in post -->\n<ins class=\"adsbygoogle\"\n     style=\"display:inline-block;width:320px;height:100px\"\n     data-ad-client=\"ca-pub-0039142346952764\"\n     data-ad-slot=\"1620587573\"><\/ins>\n<script>\n(adsbygoogle = window.adsbygoogle || []).push({});\n<\/script><\/div><style type=\"text\/css\">\r\n.ixikq6a27e40af0be6 {\r\nmargin: 5px; padding: 0px;\r\n}\r\n@media screen and (min-width: 1201px) {\r\n.ixikq6a27e40af0be6 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 993px) and (max-width: 1200px) {\r\n.ixikq6a27e40af0be6 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 769px) and (max-width: 992px) {\r\n.ixikq6a27e40af0be6 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 768px) and (max-width: 768px) {\r\n.ixikq6a27e40af0be6 {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (max-width: 767px) {\r\n.ixikq6a27e40af0be6 {\r\ndisplay: block;\r\n}\r\n}\r\n<\/style>\r\n\n<p align=\"left\">About half the participants with Parkinson\u2019s disease struggled with an aspect of memory, such as learning and retaining information, or recalling verbal information, said lead author Jared Tanner, Ph.D., an assistant research professor in the UF department of clinical and health psychology who conducted the study as part of his dissertation research for a UF doctoral degree in clinical psychology.<\/p>\n<p align=\"left\">\u201cAnd then half of those participants, or nearly one quarter of all participants with Parkinson\u2019s, were really having a difficult time consistently with their memory, enough that it would be noticeable to other people,\u201d said Tanner, adding that researchers were encouraged by the fact that most participants in the initial stages of Parkinson\u2019s were not having significant memory problems.<\/p>\n<p align=\"left\">All participants received brain scans, which used new imaging techniques that allowed the scientists to navigate the pathways of white matter fibers, the tissue through which messages travel across the brain. The methodology was developed by the research group of<a href=\"http:\/\/www.bme.ufl.edu\/people\/mareci_thomas\">Thomas Mareci, Ph.D.<\/a>, a professor of <a href=\"http:\/\/biochem.med.ufl.edu\/\">biochemistry and molecular biology in the UF College of Medicine<\/a>, and is described in a paper published July 14 in <a href=\"http:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0131493\">PLOS ONE<\/a>.<\/p>\n<p align=\"left\">Experts have theorized that cognitive problems in Parkinson\u2019s are caused by a shortage of the brain chemical dopamine, which is responsible for patients\u2019 motor issues. But with the help of imaging, the UF researchers were able to spot changes in the brain\u2019s gray and white matter that appear unrelated to dopamine loss and are specific to those patients with Parkinson\u2019s who have memory problems.<\/p>\n<p align=\"left\">\u201cNot only is gray matter important for memory, in Parkinson\u2019s disease white matter connections between the temporal lobe and a region in the posterior portion of the brain called the retrosplenial cortex were particularly important in the recall of verbal information,\u201d Tanner said. \u201cPeople with Parkinson\u2019s disease who had stronger connections between these areas of the brain did better at remembering information.\u201d<\/p>\n<p align=\"left\">Tanner\u2019s study is part of a larger research project supported by a $2.1 million grant from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health. Researchers led by Price are using imaging and cognitive testing to determine profiles for the cognitive problems that most commonly affect patients with Parkinson\u2019s. The information gleaned from the research could help clinicians foreshadow the type of cognitive impairment a patient may experience over time, if any, and tailor treatment plans accordingly.<\/p>\n<div class=\"jqiez6a27e40af0c0c\" ><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- Mobile in post -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:inline-block;width:320px;height:100px\"\r\n     data-ad-client=\"ca-pub-0039142346952764\"\r\n     data-ad-slot=\"1620587573\"><\/ins>\r\n<script>\r\n(adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><\/div><style type=\"text\/css\">\r\n.jqiez6a27e40af0c0c {\r\nmargin: 5px; padding: 0px;\r\n}\r\n@media screen and (min-width: 1201px) {\r\n.jqiez6a27e40af0c0c {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 993px) and (max-width: 1200px) {\r\n.jqiez6a27e40af0c0c {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 769px) and (max-width: 992px) {\r\n.jqiez6a27e40af0c0c {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (min-width: 768px) and (max-width: 768px) {\r\n.jqiez6a27e40af0c0c {\r\ndisplay: block;\r\n}\r\n}\r\n@media screen and (max-width: 767px) {\r\n.jqiez6a27e40af0c0c {\r\ndisplay: block;\r\n}\r\n}\r\n<\/style>\r\n","protected":false},"excerpt":{"rendered":"<p>From a recent news release\u00a0by Jill Pease at the University of Florida. Using a combination of neuropsychological testing and brain imaging, University of Florida researchers have discovered that in a group of recently-diagnosed patients with Parkinson\u2019s disease, about one quarter have significant memory problems. Parkinson\u2019s disease is commonly known as a movement disorder that leads &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.brainybehavior.com\/blog\/2015\/09\/memory-problems-in-some-with-parkinsons-disease\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Memory Problems in Some With Parkinson&#8217;s Disease&#8221;<\/span><\/a><\/p>\n","protected":false},"author":19,"featured_media":535,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,6,16,38,70],"tags":[251,273,253,268],"class_list":["post-533","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-neuroanatomy","category-neuroimaging","category-neuropsychology","category-neuroscience","category-parkinsons-disease","tag-brain","tag-entorhinal-cortex","tag-memory","tag-parkinsons-disease"],"_links":{"self":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts\/533","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/comments?post=533"}],"version-history":[{"count":3,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts\/533\/revisions"}],"predecessor-version":[{"id":538,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/posts\/533\/revisions\/538"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/media\/535"}],"wp:attachment":[{"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/media?parent=533"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/categories?post=533"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.brainybehavior.com\/blog\/wp-json\/wp\/v2\/tags?post=533"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}