Intelligence Testing Introduced

Modern intelligence testing can be traced back to Alfred Binet, a French psychologist. The French government wanted a way to identify students who would do well in school, as well as students who would not benefit from schooling. They turned to Binet in 1904 to create an unbiased, objective measure that would help the government identify the children who needed special educational assistance. Binet and his colleagues created the first modern intelligence test by focusing on abilities like problem-solving and attention.Brain and cards
From this early beginning, intelligence testing evolved with modifications by Lewis Terman, who was at Stanford, and William Stern (who created the Intelligence Quotient {IQ}). Terman modified Binet’s work and created the Stanford-Binet intelligence test. This test remains in use today (it’s gone through a number of revisions), although it is not as popular as the Wechsler Adult Intelligence Scale (WAIS).
While early tests calculated the IQ based on “mental age” and “chronological age,” IQ is no longer calculated in this manner because of the problems this (mental age) / (chronological age) formula presents in adults.
The WAIS is set to have an average score of 100 and a standard deviation of 15. This means that a person with average intelligence would have an IQ of 100 (50% of scores are higher and 50% are lower, theoretically); however, the average IQ actually falls in the range of 85 to 115. A score between 110 and 115 is considered high average and scores between 90 and 85 can be considered low average. About 96% of the population have scores between 70 and 130, with 2% below 70 and 2% above 130.
While intelligence tests are not perfect and are rightly subject to much criticism, they are still quite useful for researchers, clinicians, and educational institutions.

Image by Echoside.

Blog for a personal side to Alzheimer’s Disease

I received a nice email from someone who runs a blog about caring for her father who has Alzheimer’s disease. She provides a nice perspective from the caregiver role of what it is like to deal with this disease.

http://www.knowitalz.com

PET Scans and fMRI Compared

PET ScannerThe positron emission tomography (PET) scan measures blood flow in the brain. This is accomplished by injecting a person or animal with a radioactive isotope (i.e. an unstable atom, usually a variation of oxygen that has a short-half life); this isotope will quickly decay. Founded on the assumption that blood flow will increase in areas of the brain that are in heavy use (such as when a person is viewing an object or reading words or some other cognitive-intensive function), a fair portion of the injected isotopes will end up in the active part of the brain. As the isotopes decay, a positron (a small particle with the exact opposite charge as an electron) is released. This positron will collide with an electron and they will annihilate each other, sending two gamma ray particles in exactly opposite directions. These gamma rays are picked up by the PET scanner, which then determines where they came from in the brain. Since blood should concentrate where the brain is activated, there should be higher levels of isotopes there and this will show up on the scanner in the form of increased levels of gamma rays. The test is usually run twice (once as the control condition and once as the experimental). The difference between the two conditions is measured and any difference should show what area(s) of the brain was (or were) activated.

A PET scan is similar to an fMRI in that both measure blood flow in the brain, which is an indirect measure of brain activity. However, there are advantages and disadvantages to both functional brain imaging methods. PET scans are advantageous in that a person does not have to remain as still as he or she would for the fMRI. Tiny movements can obscure and ruin fMRI data but small movements do not affect PET scans. So, for example, with a PET scan study a researcher could have someone read out loud lists of words but the simple jaw movements would ruin the fMRI data (although this is changing to some degree as image processing becomes more sophisticated; researchers also can modify the task slightly to reduce movement artifacts in fMR images). This is really the main advantage of PET over fMRI.

PET scanning is disadvantaged compared to fMRI because the resolution of the scans is lower. PET scans can measure changes in blood flow in the brain in an area of about 5-10 cubic millimeters. fMRI can resolve down to 3 cubic millimeters and even lower as the machines become more powerful. PET scanning is also much more expensive than fMRI since it takes a special machine, radioactive isotopes, and multiple trials to get a scan. fMRI’s can be done at many hospitals around the world with little or no extra cost because of the prevalence of MRI scanners. Another disadvantage PET’s have are needing radioactive isotopes to work. This isotope can be given only a few times before it is unsafe.

While PET scans were and are better in some situations than fMRI’s, they have many disadvantages overall. With higher cost, lower spatial resolution, and need for isotopes, the disadvantages of PET scans seem to outweigh the advantages.

Image by Muffet.

Quick post

I’m really sorry for not posting as much as I would like to. I’ve been preparing for a presentation at a research conference next week (Vas-Cog) and haven’t had time to write a good post for the blog. Anyway, LiveScience has an interesting story about new research localizing visual mistake recognition in the temporal lobes. This recognition appears to occur faster than conscious awareness.

A basic introduction to fMRI and MRI

MRI scannerfMRI (functional magnetic resonance imaging) builds on a basic MRI (magnetic resonance imaging) by looking at blood flow. An MRI works because protons, which make up atoms, are affected by magnetic fields. Basically, an MRI aligns a very small proportion of the protons in body tissue (it usually affects hydrogen the most because of hydrogen’s proton and neutron composition; hydrogen is also prevalent in body tissue and so it is easy to affect). Normally the protons in hydrogen are randomly orientated which means their minute magnetic fields are also randomly orientated. When these protons are placed in the vicinity of the strong magnetic field produced by MRI machines, some of them align with the magnetic field of the machine. The machine also produces radio waves that slightly affect the aligned protons. These waves will cause the protons to spin a certain way in response to the radio waves. The radio waves are then turned off and the protons realign themselves to the magnetic field produced by the MRI machine. The machine picks up this re-alignment and a computer processes it to create an image of the brain (or what ever else is scanned). Since protons in different tissues align at different rates, the machine can differentiate between different types of tissue (such as skull and white and gray matter).

An fMRI just builds on the MRI by focusing on the ratio between oxygenated to deoxygenated blood; this is the blood oxygenation level dependent effect (BOLD effect). Basically, an fMRI indirectly measures brain activity by measuring the change in blood levels (specifically hemoglobin as it deoxygenates). An fMRI works because as brains process information blood flows to those areas to help provide the needed oxygen and glucose. The result of this process is a scan of the brain with lighter (or darker) areas where blood is flowing in greater quantity.

One example of how an fMRI was used to test a cognitive neuroscience theory was when Deibert et al. (1999) had subjects close their eyes and try to identify objects only by touch. The researchers discovered through fMRI that the subjects’ visual cortex was activated even though their eyes were closed. There were two different explanations: first the objects were identified and then visual images were created or the visual image was created during the process of identification and thus helped the subjects recognize the objects. However, fMRI alone was not sufficient to support the correct theory. When researchers used transcranial magnetic stimulation (TMS) they discovered that they could interrupt the processing in the occipital lobe and interfere with object recognition. So the combination of fMRI and TMS showed that the visual image formed during tactile exploration is important for object recognition. While fMRI was not sufficient in this case, it was key in uncovering and explaining the theory about how tactile object recognition works in the absence of visual input.

Image courtesy of MacRonin47.